James R Goldenring Selected Research

Microvillus inclusion disease

4/2021	Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations.
1/2021	Cell differentiation is disrupted by MYO5B loss through Wnt/Notch imbalance.
10/2020	Lysophosphatidic Acid Increases Maturation of Brush Borders and SGLT1 Activity in MYO5B-deficient Mice, a Model of Microvillus Inclusion Disease.
1/2020	Editing Myosin VB Gene to Create Porcine Model of Microvillus Inclusion Disease, With Microvillus-Lined Inclusions and Alterations in Sodium Transporters.
7/2014	Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease.

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James R Goldenring Research Topics

Disease

67	Metaplasia 01/2022 - 03/2002
24	Neoplasms (Cancer) 01/2022 - 03/2002
24	Stomach Neoplasms (Stomach Cancer) 01/2020 - 03/2003
18	Atrophy 01/2020 - 08/2002
12	Adenocarcinoma 02/2017 - 03/2002
11	Carcinogenesis 01/2021 - 07/2010
10	Hyperplasia 12/2020 - 02/2005
9	Inflammation (Inflammations) 11/2021 - 11/2004
8	Infections 01/2022 - 12/2007
7	Diarrhea 01/2022 - 07/2014
5	Microvillus inclusion disease 04/2021 - 07/2014
4	Gastritis 11/2021 - 08/2004
4	Ulcer 01/2018 - 01/2013
3	Atrophic Gastritis 01/2022 - 09/2011
3	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 01/2018
3	Carcinoma (Carcinomatosis) 01/2021 - 09/2010
3	Necrosis 11/2013 - 03/2006
2	Stomach Ulcer (Gastric Ulcer) 11/2021 - 09/2016
1	Confusion (Bewilderment) 01/2022
1	Polyps 12/2021
1	Hemorrhage 11/2021
1	Precancerous Conditions 01/2021
1	Fibrosis (Cirrhosis) 01/2021
1	Colonic Neoplasms (Colon Cancer) 01/2020
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2019

Drug/Important Bio-Agent (IBA)

59	spasmolytic polypeptideIBA 01/2022 - 03/2002
17	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2003
12	DMP 777IBA 01/2021 - 03/2006
9	Biomarkers (Surrogate Marker)IBA 01/2020 - 05/2005
6	Tamoxifen FDA LinkGeneric 01/2021 - 12/2012
5	AcidsIBA 01/2022 - 03/2006
5	Pharmaceutical PreparationsIBA 01/2022 - 04/2006
5	CytokinesIBA 01/2020 - 09/2014
4	EnzymesIBA 01/2022 - 09/2011
4	Myosins (Myosin)IBA 01/2021 - 07/2014
4	CarcinogensIBA 10/2019 - 08/2002
4	Trefoil FactorsIBA 09/2016 - 08/2004
4	AntibodiesIBA 05/2013 - 10/2002
3	SodiumIBA 01/2022 - 01/2017
3	Interleukin-33IBA 01/2021 - 01/2018
3	Interleukin-5 (Interleukin 5)IBA 01/2021 - 01/2018
3	AmphiregulinIBA 01/2019 - 05/2007
3	Intrinsic Factor FDA Link 01/2019 - 12/2007
3	Acetic Acid (Vinegar)FDA LinkGeneric 01/2017 - 01/2013
3	Transcription Factors (Transcription Factor)IBA 01/2016 - 09/2010
3	GastrinsIBA 12/2012 - 02/2005
2	AntralIBA 01/2022 - 09/2006
2	InterleukinsIBA 01/2021 - 01/2018
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2012
2	Interleukin-13IBA 12/2020 - 01/2018
2	MicroRNAs (MicroRNA)IBA 01/2020 - 01/2016
2	Adenosine Triphosphatases (ATPase)IBA 01/2020 - 03/2006
2	IntegrinsIBA 10/2019 - 02/2011
2	LectinsIBA 01/2019 - 01/2019
2	Monomeric GTP-Binding ProteinsIBA 01/2019 - 09/2014
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019 - 04/2016
2	ErbB Receptors (EGF Receptor)IBA 12/2018 - 04/2006
2	Enzyme Precursors (Zymogens)IBA 01/2018 - 07/2017
2	Phenobarbital (Luminal)FDA Link 04/2015 - 03/2006
2	Cytotoxins (Cytolysins)IBA 11/2013 - 01/2013
2	trimethylaminocarboxyldihydroboran (TCDB)IBA 11/2013 - 01/2012
2	Clostridium difficile toxB proteinIBA 11/2013 - 01/2012
2	Peptides (Polypeptides)IBA 11/2012 - 06/2003
2	ParaffinIBA 11/2012 - 01/2007
2	Galectin 4 (LGALS4)IBA 04/2012 - 07/2010
2	Transforming Growth Factor alpha (TGF-alpha)IBA 05/2007 - 05/2005
2	prothymosin alphaIBA 01/2007 - 08/2004
1	Small Cytoplasmic RNAIBA 01/2022
1	Aquaporin 5IBA 01/2022
1	MucinsIBA 01/2022
1	Calcibiotic Root Canal SealerIBA 12/2021
1	Fibronectins (Fibronectin)IBA 11/2021
1	Messenger RNA (mRNA)IBA 11/2021
1	Neurofibromin 2 (Merlin)IBA 01/2021
1	CateninsIBA 01/2021
1	4-(4-sulfophenylazo)-2-mercuriphenol (SAMP)IBA 01/2021
1	lysophosphatidic acidIBA 10/2020
1	Lysophosphatidic Acid ReceptorsIBA 10/2020
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2020
1	LuciferasesIBA 01/2020
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2020
1	Interleukin-27 (Interleukin 27)IBA 01/2020
1	Type IV Secretion SystemsIBA 01/2019
1	rab11 proteinIBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Leucine (L-Leucine)FDA Link 01/2019
1	Oncogene Proteins (Oncogene Protein)IBA 01/2019
1	ClathrinIBA 01/2019
1	Diacylglycerol O-AcyltransferaseIBA 11/2018
1	Type 4 Fibroblast Growth Factor ReceptorIBA 05/2018
1	Smad4 ProteinIBA 01/2018
1	Drinking WaterIBA 01/2018
1	Neutralizing AntibodiesIBA 01/2018
1	AlarminsIBA 01/2018
1	Interleukin-17 (Interleukin 17)IBA 01/2018

Therapy/Procedure

4	Therapeutics 05/2018 - 04/2006
2	Lasers (Laser) 01/2016 - 06/2003
1	Fat-Restricted Diet (Diet, Fat Restricted) 11/2018
1	Diet Therapy (Therapy, Diet) 06/2018
1	Transplantation 05/2018